The Anezsky klaster is the first Early Gothic building in Prague (founded 1234) - something notable in a city filled with amazingly well-preserved examples of Gothic architecture such as St Vitus, the Charles Bridge and the Powder Tower. Over the years the complex's convent, chapels and several churches deteriorated and in some cases, were completely destroyed. After Habsburg emperor Josef II's religious reforms, the convent was shut down in 1782 and converted into lodgings for the poor. St Anežka, (Sv. Anežka česká) who is pictured on the pink 50 Kč banknote, is the patron saint of Bohemia and founder of the convent complex. She was a daughter of the ruling Premyslid family, but no wallflower in terms of her activism, intelligence and energy. St Francis of Assisi, after whom one of the churches in the complex is named, founded his religious order in 1209 without the sort of financial backing earlier orders had enjoyed. As communism was crumbling, the remaining religious leadership, decimated over years by Communism's anti-religious influence, lobbied the Vatican to finally declare Anežka a saint. This happened 12 November 1989, though Anežka's niece Elizabeth had started the process in 1328! Today, the convent is used to house part of the Czech National Gallery's collection.

The convent of Saint Agnes (Czech: Anežský klášter) is situated on the right bank of Vltava, in Prague Old Town area called „Na Františku“. The monastery of Poor Clares of the Order of Saint Clare and Franciscans was founded in 1231 by Agnes of Bohemia, who also became the abbess of the convent.