A prominent, 261m tall hotel located right next to the famed Casino Lisboa, effectively an extension of it. It's the tallest building in Macau and with the lotus shape also most distinctive part of its skyline. Inside, a 218 carat diamond The Star of Stanley Ho is on permanent display.

Grand Lisboa (Chinese: 新葡京, Portuguese: Grande Lisboa) is a 47-floor, 261-metre-tall (856 ft) hotel in Sé, Macau. It is owned and operated by Sociedade de Jogos de Macau and was designed by Hong Kong architects Dennis Lau and Ng Chun Man with the interiors created by Khuan Chew, Design Principal of KCA International. Its casino and restaurants were opened on February 11, 2007, while the hotel was opened in December 2008. The casino offers 800 gaming tables and 1,000 slot machines. The hotel contains 430 hotel rooms and suites. The Grand Lisboa is the tallest building in Macau and the most distinctive part of its skyline.

The casino is the first in Macau to offer Texas hold 'em poker ring games. It was also the first to offer craps, though several other casinos in Macau now offer the game.

In 2017 it was reported that the Grand Lisboa suffered a decline in revenue and profits during 2016.