The grand old dame of Macau's casinos, the Lisboa offers an older world feel on its gaming floors, structured in a labyrinth of different clubs and rooms for various levels of play, with displays of antiques owned by the late gambling tycoon Stanley Ho. Tables play in both MOP and HKD.

Casino Lisboa is an integrated resort located in Sé, Macau, operated by SJM Holdings. This three-storey complex was built in late 1960s. The original casino and the 12-storey round hotel tower were built in 1970 by Stanley Ho, Teddy Yip, Yip Hon and Henry Fok. A 270-room extension was added in 1991 for a total of 927 rooms. In 2006, another extension, the Grand Lisboa, was built next to the current complex. Therefore, a total of 2,362 rooms are in place at Hotel Lisboa as of 2010. This expansion was partly done in competition with the then newly opened Wynn Macau, located right next to the original Casino Lisboa.