Built in the 1600s on top of Guia Hill on the eastern part of the peninsula, the fortress's main function was to ward off any attack by China. Within the fortress is the Chapel of Our Lady of Guia and the 15 m-tall Guia Lighthouse, said to be the first modern lighthouse on the Chinese coast. Guia Fortress can be reached by the Guia Cable Car (Teleférico da Guia) just outside the entrance of the Flora Garden on Rua do Túnel, off Av Sidónio Pais.

The Guia Fortress is a 17th-century colonial military fort, chapel, and lighthouse complex in São Lázaro, Macau. The complex is part of the UNESCO World Heritage Site Historic Centre of Macau. The view of the fortress and the lighthouse has been blocked by the Macau Liaison Office since 2010, which is seen by local citizens and scholars as an example that the conservation of heritage in urban planning was ignored by the Macao government.